Thought Disorder in Schizophrenia : Editor ' s Introduction

by Philip S. Holzman Investigations into the biology of schizophrenia and of the affective disorders have yielded valuable information about psychotic conditions. Two events have sparked this progress. The first was the introduction of the phenothiazines and the mood-altering drugs in the early 1950s, an event that produced testable biological theories about the drugs' action. The second was the set of two critical reviews of the biological studies of psychosis by Seymour S. Kety (1959), which exposed the many methodological errors that had marred biological studies of psychosis up to that time, and established the standard for acceptable experimentation in this area.